Hi Txmomma :)
In my honest opinion, I believe this is more a matter of the Alzheimer's diagnosis rather than a reluctant hoarder/messy situation. My suggestion is to contact an Alzheimer's support group message board for better advice than we can offer here. Yes, they should have a safe and sanitary home and hopefully you can learn the best way to help them achieve this without your mother getting too upset.
Best wishes to all of you through this challenging time.
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